Pathogenesis, Symptoms and Diagnosis, and Prevention of Dengue Hemorrhagic Fever in Adults
DOI:
https://doi.org/10.62872/s0z09w04Keywords:
dengue haemorrhagic fever, pathogenesis of DHF, symtoms and diagnosis of DHFAbstract
Dengue Hemorrhagic Fever (DHF) is an infectious disease caused by the dengue virus, characterized by symptoms such as fever, muscle or joint pain, leukopenia, rash, lymphadenopathy, thrombocytopenia, and hemorrhagic tendencies. In DHF, there is plasma leakage leading to fluid accumulation in body cavities, and in severe cases, it can progress to Dengue Shock Syndrome, characterized by shock. The illness is mainly spread by Aedes aegypti and Aedes albopictus mosquitoes, presenting a substantial worldwide health issue. The diagnosis of DHF requires the presence of several criteria: fever or recent history of acute fever lasting 2-7 days, often biphasic; at least one hemorrhagic manifestation such as positive tourniquet test, ecchymosis, mucosal bleeding, hematemesis, or thrombocytopenia; and evidence of plasma leakage. Young adults are particularly susceptible to dengue fever due to their frequent outdoor activities. In Padang City, West Sumatra Province, in 2020, the age group most affected by the disease was adults aged 15 to 44 years.
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Agustini II., Bangkele EY, Salman M., & Munir M. (2018). Karakteristik Pasien Demam Berdarah Dengue (DBD) Pada Ruang Rawat Inap Anak Di RSUD Undata Palu Tahun 2017. 5(3); 49 – 58.2. Medika Tadulako Jurnal Ilmiah Kedokteran, 5(3), 490–582.
Anderson KB, Gibbons R V., Cummings DAT, Nisalak A, Green S, Libraty DH, et al. (2014). A shorter time interval between first and second dengue infections is associated with protection from clinical Illness in a school-based cohort in Thailand. J Infect Dis, 209(3), 360–368.
Begum F, Das S, Mukherjee D, Mal S., & Ray U. (2019). Wawasan Tropisme virus Dengue pada manusia. Virus, 11(12), 1136.
Bhatt P, Sabeena SP, Varma M., & Arunkumar G. (2021). Pemahaman Terkini Tentang Patogenesis Infeksi Virus Dengue. Mikrobiol, 78(1), 17–32.
Candra, Arya (2020). Demam Berdarah Dengue: Epidemiologi, Patogenesis, dan Faktor Risiko Penularan. Aspirator, 2(2), 110–119. https://doi.org/10.22435/aspirator.v2i2.2951
Darwis D. (1999). Kegawatan Demam Berdarah Dengue Pada Anak. Naskah lengkap, pelatihan bagi dokter spesialis anak dan dokter spesialis penyakit dalam pada tata laksana kasus DBD. Penerbit Fakultas Kedokteran Universitas Indonesia.
Das S, Abreu C, Harris M, Shrader J, S. S. (2022). Severe Thrombocytopenia Associated with Dengue Fever: An Evidence-Based Approach to Management of Thrombocytopenia. Case Rep Hemato, 1–3.
Dinkes Padang. (2022). Kasus DBD di Kota Padang Naik dari Tahun Lalu, Dinkes Sebut Didominasi Derita Orang Dewasa. https://www.padang.go.id/kasus-dbd-di-kota-padang-naik-dari-tahun-lalu-dink es-sebut-didominasi-derita-orang-dewasa
Halstead SB. (2019). Recent Advances in Understanding Dengue. 1000 Res 2019, 8. https://doi.org/doi:10.12688/f1000research. 19197.1.
Hidayat, W. A., Yaswir, R., & Murni, A. W. (2017). Hubungan Jumlah Trombosit dengan Nilai Hematokrit pada Penderita Demam Berdarah Dengue dengan Manifestasi Perdarahan Spontan di RSUP Dr. M. Djamil Padang. Jurnal Kesehatan Andalas, 6(2), 446–451.
Hukom, A. O. E., Warouw, S. M., Memah, M., & Mongan, A. E. (2013). Hubungan Nilai Hematokrit dan Nilai Jumlah Trombosit Pada Pasien Demam Berdarah Dengue. Jurnal E-Biomedik, 1(1), 707–711.
Jayani I, F. C. (2019). Status Gizi Berhubungan dengan Derajat Klinik Infeksi Dengue Hemorrhagic Fever (DHF). Nursing Sciences Journal, 1(1), 1–10.
Kementrian Kesehatan RI. (2017). Pedoman Demam Berdarah Dengue.
Kementrian Kesehatan RI. (2020a). Kasus DBD di Indonesia.
Kementrian Kesehatan RI. (2020b). Profil Kesehatan Indonesia Tahun 2019.
Kementrian Kesehatan RI. (2021a). Data Kasus Terbaru DBD di Indonesia. Sehat Negeriku. https://sehatnegeriku.kemkes.go.id/baca/umum/20201203/2335899/data-kasus-terbaru-dbd-indonesia/
Kementrian Kesehatan RI. (2021b). Strategi Nasional Penanggulangan Dengue 2021-2025.
Kementrian Kesehatan RI. (2011). Tata Laksana Demam Berdarah Dengue.
Kementrian Kesehatan RI. (2020a). Keputusan Menteri Kesehatan Republik Indonesia Nomor HK.01.07/MENKES/9845/2020 Tentang Pedoman Nasional Pelayanan Kedokteran Tata Laksana Infeksi Dengue Pada Dewasa. Scrib.com/document/556747440/PNPK-Tata Laksana Infeksi Dengye Pada dewasa-2
Kementrian Kesehatan RI. (2020b). Pedoman Nasional Pelayanan Kedokteran Tata Laksana Infeksi Dengue pada Dewasa.https://yankes.kemkes.go.id/unduhan/fileunduhan_1610413358_685089.pdf
Kementrian Kesehatan RI. (2023). Demam Berdarah Dengue 2022. P2P Kemenkes. http:/p2p,kemkes.go.id
Misnardiarly. (2009). Demam Berdarah Dengue (DBD). Pustaka Populer Obor.
Nababan, Willy Medi Christian. (2023). Kasus Kematian akibat Demam Berdarah Dengue Didominasi Anakanak. Kompas.https://www.kompas.id/baca/humaniora/2023/02/05/73-persen-kematian-dbd-terjadi-pada-anak
Sandra, T., Safro, M. A., Suhartono, S., Martini, M., & Hadisaputro, S. (2019). Berbagai Faktor Yang Berpengaruh Terhadap Kejadian Demam Berdarah Dengue Pada Anak Usia 6-12 Tahun (Studi Di Kecamatan Tembalang). Jurnal Epidemiologi Kesehatan Komunitas, 4(1). https://doi.org/https://doi.org/10.14710/jekk.v4i1.4423
Soegijanto, Soegeng. (2002). Patogenesa dan Perubahan Fisiologi Infeksi Virus Dengue. Pediatrikcom Buletin. http://www.pediatrikcom/buletin/20060220-8ma2gi-buletindoc
Soegijanto S. (2006). Patogenesa dan Perubahan Patofisiologi Infeksi Virus Dengue. www.pediatrikcom/buletin/20060220-%0A8ma2gi-buletindoc; 2002 [cited 2010]; %0AAvailable from: www.pediatrikcom/%0Abuletin/20060220-8ma2gi-buletindocNo Title
Steven T Stoddard, Brett M Forshey, Amy C Morrison, Valerie A Paz-Soldan, Gonzalo M Vazquez-Prokopec, Helvio Astete, Robert C Reiner Jr, Stalin Vilcarromero, John P Elder, Eric S Halsey, Tadeusz J Kochel, Uriel Kitron, T. W. S. (2013). House-to-House Human Movement Drives Dengue Virus Transmission. National Library of Medicine, 110(3), 994–999. https://doi.org/10.1073/pnas.1213349110
Suhendro, Nainggolan, L., Chen, K., & Pohan, H. T. (2014). Demam Berdarah Dengue dalam Dalam: Sudoyo AW, Setiyohadi B, Alwi I, Kolopaking MS, Setiati S, editor. Buku Ajar Ilmu Penyakit Dalam Edisi VI (S. Setiati, I. Alwi, A. W. Sudoyo, M. Simadibrata K, B. Setiyohadi, & A. F. Syam (eds.); VI). InternaPublishing.
Sukohar A. (2014). Demam Berdarah Dengue. Medula, 2(2), 1–15.
Suwandono A. (2019). Dengue Update: Menilik Perjalanan Dengue di Jawa Barat. 2019.
Syumarta, Y., Hanif, A. M., & Rustam, E. (2014). Hubungan Jumlah Trombosit, Hematokrit dan Hemoglobin dengan Derajat Klinik Demam Berdarah Dengue pada Pasien Dewasa di RSUP. M. Djamil Padang. Jurnal Kesehatan Andalas., 3(3), 492–498.
Vebriani, L., Wardana, Z., & Fridayenti. (2016). Karakteristik Hematologi Pasien Demam Berdarah Dengue di Bagian Penyakit Dalam RSUD Arifin Achmad Provinsi Riau Periode 1 Januari – 31 Desember 2013. Jom FK, 3(1).
WHO. (1997). Demam Berdarah Dengue: Diagnosis, Pengobatan, Pencegahan dan Pengendalian (2nd ed.). WHO.
WHO. (2023). Dengue and severe dengue. Global Regions. https://www.who.int/news-room/fact-sheets/detail/dengue-and-severe-dengue
Word Health Organization. (2012). Global strategy for dengue prevention and control 2012-2020. : World Health Organization.
Word Health Organization. (2020). Dengue and Severe Dengue. https;//www.who.int/news-room/fact-sheets/detail/dengue-and-severe-dengue
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Copyright (c) 2024 Rosmaini Rosmaini, Erdanela Setiawati (Author)
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This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
